Ryan Brewster Follow. Verbal memory deficits are among the most prominent cognitive sequelae in individuals with left temporal lobe epilepsy LTLE. However, relationships between verbal memory function and white matter integrity WMI in the left temporal lobe remain unclear. LTLE and RTLE groups did not differ significantly on measures of verbal memory until analyses were restricted to participants with left-lateralized language functioning.
CURE Discovery: Temporal Lobe Epilepsy and Memory Impairment
Temporal Lobe Epilepsy | Epilepsy Foundation
The International League Against Epilepsy ILAE and the International Bureau for Epilepsy IBE define epilepsy as a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures and by the biologic, cognitive, psychological, and social consequences of this condition. This association may reflect the anatomical and neurobiological source of both epileptic seizures and the behavioral manifestations. Antiepileptic drugs AEDs can play a role in the genesis of psychiatric symptoms; on the other hand, some psychotropic medications can lower the seizure threshold and provoke epileptic seizures. Indeed, there is a general agreement that the incidence of neurobehavioral disorders is higher in patients with epilepsy than in the general population, although some authors argue that this apparent overrepresentation is due to sampling errors or inadequate control groups.
A review of the epidemiology of temporal lobe epilepsy
Home » Proposal » Hrct temporal bone thesis proposal. In many patients with epilepsy antiepileptic drug treatment is unable to control the seizures. Using a dedicated MRI-protocol, it is possible to detect an epileptogenic lesion in 80 percent of these patients. Resection of these lesions can lead to seizure freedom in many patients.
We study spatiotemporal patterns of neuronal activity that are generated in the brain. This collective neuronal firing not only underlies thought and memory, but also is essential to our understanding of neurological disease. We develop advanced optical techniques for recording neuronal activity in a variety of experimental models to understand how network firing codes for information, is shaped through learning, and becomes altered in diseases of the nervous system.